304350 - Medicinal Chemistry 1 |
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Credit Hours2 Pre-requisite304250 Co-requisite. Distribution2 + 0 |
This course provides students with an introduction to the molecular bases of drug action. It provides the knowledge of the relationship between pharmaceutical compounds and their physicochemical properties (relation to absorption, distribution, and elimination). It focuses on the basic knowledge of drug-receptor interaction, types of chemical bonds involved in drug-receptor interactions, drug mechanism of action, and drug metabolism. Also, this course emphasizes on the stereochemistry (optical, geometrical, and conformational isomerism) of different pharmaceutical compounds in relation to their pharmacological activity. Finally, this course provides the basic concepts of prodrug action and drug discovery. |